Information about programs that are known to experience a loss of functionality when they run on a Windows Vista Service Pack 1-based computer

Service Pack 1 for Windows Vista is an important update for Windows Vista. Windows Vista Service Pack 1 (SP1) contains many security, reliability, and feature updates for Windows Vista. A program may experience a loss of functionality after you install Windows Vista SP1. However, most programs will continue to work as expected after you install Windows Vista SP1.

Currently, 6 applications are blocked from running, and 3 do not run, and 3 do not run properly.

You can read more about it here.